Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304312 | 0.88 | KMT2A (0.40) | CXCR3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL325167 | 0.85 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL3378801 | 0.82 | PIK3CG (0.43) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL3378381 | 0.81 | MEN1 (0.42) | CXCR3MEN1KMT2AHTTLMNA | |
| SCHEMBL303882 | 0.81 | KMT2A (0.40) | CXCR3MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL303301 | 0.81 | MEN1 (0.41) | CXCR3MEN1KMT2AALDH1A1HTT | |
| SCHEMBL304106 | 0.80 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNATRPM8 | |
| SCHEMBL302499 | 0.79 | PIK3CG (0.41) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL2211916 | 0.79 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNATRPM8 | |
| SCHEMBL2211492 | 0.79 | MEN1 (0.53) | CXCR3MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010023448-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |