SCHEMBL303882

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL304312	0.91	KMT2A (0.40)	KMT2ADRD4MEN1ALDH1A1LMNA
	SCHEMBL303301	0.90	MEN1 (0.41)	KMT2AMEN1ALDH1A1LMNAPOLB
	SCHEMBL2211916	0.88	MEN1 (0.42)	KMT2AMEN1ALDH1A1LMNAPOLB
	SCHEMBL303432	0.87	LMNA (0.42)	KMT2AMEN1ALDH1A1LMNAPOLB
	SCHEMBL3378801	0.86	PIK3CG (0.43)	KMT2ADRD4MEN1ALDH1A1HPGD
	SCHEMBL2214837	0.85	MEN1 (0.44)	KMT2ADRD4MEN1ALDH1A1KDM4E
	SCHEMBL2212260	0.85	LMNA (0.40)	KMT2AMEN1ALDH1A1HPGDLMNA
	SCHEMBL2214180	0.85	MEN1 (0.54)	KMT2AMEN1ALDH1A1LMNAPOLB
	SCHEMBL3377043	0.84	MEN1 (0.47)	KMT2AMEN1ALDH1A1KDM4EGAA
	SCHEMBL302949	0.84	MEN1 (0.49)	KMT2AMEN1ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.