Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621408 | 0.84 | TDP1 (0.66) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL22095171 | 0.82 | HTT (0.54) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL22672667 | 0.81 | TDP1 (0.62) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29151067 | 0.81 | TDP1 (0.62) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18423031 | 0.81 | TDP1 (0.62) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL1133972 | 0.80 | GRM1 (0.68) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4348032 | 0.78 | TDP1 (1.00) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL31133324 | 0.78 | TDP1 (1.00) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL8177959 | 0.76 | ALDH1A1 (0.62) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL999160 | 0.75 | TDP1 (0.58) | TDP1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123482-A1 | SMALL MOLECULE INHIBITION OF SULFOTRANSFERASE SULT1A3 | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-06-18 | — | — | WO | disclosed |