Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.49 |
| ▸ | TK1 | P04183 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257989 | 1.00 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| SCHEMBL18516930 | 0.90 | ADORA3 (0.51) | ADORA3HPRT1TK1PNPBLM | |
| SCHEMBL15197991 | 0.90 | ADORA3 (0.51) | ADORA3HPRT1TK1PNPBLM | |
| SCHEMBL880159 | 0.90 | ADORA3 (0.51) | ADORA3HPRT1TK1PNPBLM | |
| Entecavir Anhydrous SCHEMBL21347868 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| SCHEMBL9223882 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| Entecavir Anhydrous SCHEMBL28648 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| Entecavir Anhydrous SCHEMBL21510623 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| Entecavir Anhydrous SCHEMBL24726395 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM | |
| Entecavir Anhydrous SCHEMBL19644968 | 0.86 | ADORA3 (0.52) | ADORA3HPRT1TK1PNPBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020121122-A1 | CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS | Janssen Biopharma, Inc. (US) | 2020-06-18 | — | — | WO | disclosed |