Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.49 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695437 | 0.97 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30099681 | 0.97 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30292792 | 0.97 | PTGS1 (0.52) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL29695622 | 0.96 | GLO1 (0.49) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30099464 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30099536 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30099480 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL29742960 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL30099519 | 0.93 | GLO1 (0.48) | PTGS1GSTK1GLO1FOLH1RIMKLA | |
| SCHEMBL29526001 | 0.93 | PTGS1 (0.50) | PTGS1GSTK1GLO1FOLH1RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |