Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 18/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105742 | 0.89 | P2RX3 (0.33) | P2RX3PDE5A | |
| SCHEMBL22105423 | 0.86 | P2RX3 (0.35) | P2RX3PDE5A | |
| SCHEMBL25996795 | 0.82 | P2RX3 (0.39) | P2RX3 | |
| SCHEMBL22105849 | 0.81 | P2RX3 (0.35) | P2RX3PDE5A | |
| SCHEMBL24091847 | 0.80 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL24495601 | 0.80 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL22105469 | 0.80 | P2RX3 (0.45) | P2RX3PDE5A | |
| SCHEMBL22105394 | 0.79 | P2RX3 (0.45) | P2RX3PDE5A | |
| SCHEMBL24091844 | 0.79 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL22105603 | 0.78 | P2RX3 (0.45) | P2RX3PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894410-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2023-10-11 | — | — | EP | disclosed |
| WO-2020120450-A1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-18 | — | — | WO | disclosed |