SCHEMBL2211145

SCHEMBL2211145

CC(C)N1CCC(Oc2ccc3nc(OC(=O)NCCC4CCOCC4)ccc3c2)CC1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2206296 0.95 HRH3 (0.52) HRH3
SCHEMBL1377273 0.87 HRH3 (0.67) HRH3
SCHEMBL2208864 0.84 HRH3 (0.58) HRH3
SCHEMBL2242065 0.83 HRH3 (0.57) HRH3
SCHEMBL1379726 0.82 HRH3 (0.60) HRH3
SCHEMBL2209576 0.82 HRH3 (0.53) HRH3
SCHEMBL2212983 0.82 HRH3 (0.59) HRH3
SCHEMBL2211506 0.79 HRH3 (0.52) HRH3
SCHEMBL2212122 0.78 HRH3 (0.51) HRH3
SCHEMBL2213201 0.78 PDE3B (0.50) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1805166-B1 QUINOLINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2011-07-27 EP claimed