Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12766860 | 0.84 | KDR (0.72) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1499334 | 0.82 | KDR (0.67) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1496372 | 0.82 | MAPT (0.61) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1499586 | 0.82 | MAPT (0.61) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL12409539 | 0.82 | KMT2A (0.62) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1499486 | 0.81 | KDR (0.68) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1499559 | 0.81 | KDR (0.65) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL18049886 | 0.80 | KDR (0.83) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL12838300 | 0.80 | KDR (0.66) | KDRMAPTDHODHKMT2AMEN1 | |
| SCHEMBL1499290 | 0.79 | KDR (0.63) | KDRMAPTDHODHKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235000-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2020-06-17 | — | — | EP | disclosed |