Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499586 | 0.85 | MAPT (0.61) | MAPTKDRDHODHTRPV1NPC1 | |
| SCHEMBL22112263 | 0.82 | KDR (0.68) | MAPTKDRDHODHTRPV1NPC1 | |
| SCHEMBL1496356 | 0.81 | TRPV1 (0.59) | MAPTKDRTRPV1NPC1RAB9A | |
| SCHEMBL21938284 | 0.80 | MEN1 (0.73) | MAPTNPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL13175094 | 0.79 | PRKCI (0.67) | MAPTRAB9AKMT2AMEN1HTT | |
| SCHEMBL12766860 | 0.79 | KDR (0.72) | MAPTKDRDHODHTRPV1NPC1 | |
| SCHEMBL2533682 | 0.79 | NPC1 (0.71) | MAPTTRPV1NPC1RAB9AL3MBTL1 | |
| SCHEMBL30904871 | 0.79 | NPC1 (0.71) | MAPTTRPV1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1496330 | 0.78 | NPC1 (0.61) | MAPTKDRDHODHTRPV1NPC1 | |
| SCHEMBL13237113 | 0.77 | MAPT (0.67) | MAPTKDRDHODHTRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897774-B2 | Cyclic compound having quinolylalkylthio group | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080021064-A1 | Novel cyclic compound having quinolylalkylthio group | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021064-A1 | Novel cyclic compound having quinolylalkylthio group | SQOR, QSOX1, SQLE | MAPT 4673/4885KDR 3463/4885DHODH 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.