Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 3/20 | 0.75 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044398 | 0.91 | MAPT (0.64) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL10049796 | 0.91 | MAPT (0.64) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL607853 | 0.86 | MAPT (1.00) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL25440088 | 0.85 | MAPT (0.58) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL338452 | 0.84 | CLK4 (0.64) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL31674641 | 0.84 | KDM4E (0.56) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL31674651 | 0.84 | MAPT (0.56) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL31674628 | 0.84 | MAPT (0.56) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL31674630 | 0.84 | MAPT (0.56) | MAPTKDM4ETP53CLK4XDH | |
| SCHEMBL2876553 | 0.82 | CLK4 (0.61) | MAPTKDM4ETP53CLK4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190293-A1 | RUBBER COMPOSITION, METHOD FOR MANUFACTURING RUBBER COMPOSITION, AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-06-18 | — | — | US | disclosed |