Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967103 | 0.90 | KMT2A (0.47) | KMT2AMEN1HDAC6HDAC3HDAC1 | |
| SCHEMBL1499521 | 0.89 | HDAC6 (0.50) | KMT2AMEN1NAMPTHDAC6HDAC3 | |
| SCHEMBL1499516 | 0.89 | HDAC6 (0.50) | KMT2AMEN1NAMPTHDAC6HDAC3 | |
| SCHEMBL29973275 | 0.86 | SMN1; SMN2 (0.51) | KMT2AMEN1NAMPTHDAC3HDAC1 | |
| SCHEMBL1499583 | 0.86 | SMN1; SMN2 (0.51) | KMT2AMEN1NAMPTHDAC3HDAC1 | |
| SCHEMBL1499581 | 0.86 | SMN1; SMN2 (0.51) | KMT2AMEN1NAMPTHDAC3HDAC1 | |
| SCHEMBL1499328 | 0.80 | IGF1R (0.44) | KMT2AMEN1HDAC6HDAC3HDAC1 | |
| SCHEMBL1499529 | 0.80 | IGF1R (0.44) | KMT2AMEN1HDAC6HDAC3HDAC1 | |
| SCHEMBL1499327 | 0.80 | IGF1R (0.44) | KMT2AMEN1HDAC6HDAC3HDAC1 | |
| SCHEMBL1499526 | 0.80 | IGF1R (0.44) | KMT2AMEN1HDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235000-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2020-06-17 | — | — | EP | disclosed |