SCHEMBL2211276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2208883	0.91	GCK (0.57)	GCK
	SCHEMBL2215330	0.90	GCK (0.56)	GCKMEN1KMT2APOLBLMNA
	SCHEMBL2212669	0.87	GCK (0.57)	GCKSMN1; SMN2
	SCHEMBL2210696	0.86	GCK (0.56)	GCKMEN1KMT2A
	SCHEMBL2663157	0.86	GCK (0.56)	GCK
	SCHEMBL2213345	0.86	GCK (0.59)	GCKSMN1; SMN2HSD17B10POLB
	SCHEMBL2213370	0.86	GCK (0.73)	GCKMEN1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL2212557	0.86	GCK (0.73)	GCKSMN1; SMN2TSHRPOLBLMNA
	SCHEMBL2208913	0.86	GCK (0.62)	GCKMEN1KMT2ASMN1; SMN2LMNA
	SCHEMBL2215580	0.86	GCK (0.55)	GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.