SCHEMBL2211461

SCHEMBL2211461

C(/C=C/c1ccc(N(c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)c2ccc(/C=C/C=C(c3ccccc3)c3ccccc3)cc2)cc1)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.45
CYP11B2 P19099 2/20 0.45
PTGS2 P35354 4/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4E B2RXH2 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2212093 1.00 CYP19A1 (0.45) CYP19A1CYP11B2PTGS2ESR1ESR2
SCHEMBL2212097 1.00 CYP19A1 (0.45) CYP19A1CYP11B2PTGS2ESR1ESR2
SCHEMBL2211464 1.00 CYP19A1 (0.45) CYP19A1CYP11B2PTGS2ESR1ESR2
SCHEMBL2049529 0.98 CYP19A1 (0.44) CYP19A1CYP11B2PTGS2ESR1ESR2
SCHEMBL2049530 0.98 CYP19A1 (0.44) CYP19A1CYP11B2PTGS2ESR1ESR2
SCHEMBL2166590 0.94 LMNA (0.40) ALDH1A1MAPTMAPK1L3MBTL1LMNA
SCHEMBL2210691 0.94 LMNA (0.40) ALDH1A1MAPTMAPK1L3MBTL1LMNA
SCHEMBL21029553 0.94 LMNA (0.40) ALDH1A1MAPTMAPK1L3MBTL1LMNA
SCHEMBL6140221 0.92 LMNA (0.39) ALDH1A1MAPTL3MBTL1LMNACYP2D6
SCHEMBL12284421 0.92 LMNA (0.39) ALDH1A1MAPTL3MBTL1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP claimed
US-8007971-B2 Tris(enylaryl)amine containing photoconductors XEROX CORPORATION (US) 2011-08-30 US claimed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-20090325096-A1 TRIS(ENYLARYL)AMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP disclosed
US-8007971-B2 Tris(enylaryl)amine containing photoconductors XEROX CORPORATION (US) 2011-08-30 US disclosed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US disclosed
US-20090325096-A1 TRIS(ENYLARYL)AMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US disclosed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US disclosed