Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 14/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22115107 | 0.91 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL22115109 | 0.89 | FGFR1 (0.54) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL22114567 | 0.89 | FGFR4 (0.58) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL22114538 | 0.88 | FGFR1 (0.58) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL22114936 | 0.88 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL22114829 | 0.84 | FGFR1 (0.57) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL22114939 | 0.84 | FGFR4 (0.53) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL30212062 | 0.84 | FGFR4 (0.60) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL22321454 | 0.84 | FGFR4 (0.60) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL22114923 | 0.82 | FGFR1 (0.60) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119606-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |