SCHEMBL22115308

SCHEMBL22115308

N#Cc1ccc(-c2cc(Cl)ccc2F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.45
TMPRSS4 Q9NRS4 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
PTGS1 P23219 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
NLRP3 Q96P20 1/20 0.42
TRPA1 O75762 2/20 0.42
GSK3B P49841 1/20 0.41
MAP2 P11137 1/20 0.40
KMT2A Q03164 1/20 0.40
MMP3 P08254 1/20 0.39
MDM2 Q00987 1/20 0.39
PGR P06401 1/20 0.39
MAPKAPK2 P49137 1/20 0.39
EGLN2 Q96KS0 2/20 0.39
ACLY P53396 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20794066 0.85 TMPRSS4 (0.43) TMPRSS4MAOAMAOBLMNAMAPT
SCHEMBL19579048 0.82 KIF11 (0.52) KIF11PTGS1TSHRMMP3EGLN2
SCHEMBL22115305 0.81 PTGDR2 (0.54) MAOBLMNAMAPTHTTKMT2A
SCHEMBL19579265 0.80 KIF11 (0.50) KIF11PTGS1MMP3EGLN2ACLY
SCHEMBL20793997 0.80 EGLN2 (0.44) TMPRSS4MAOAMAOBLMNAMAPT
SCHEMBL2650216 0.80 MAP4K4 (0.44) KIF11PTGS1MMP3PGREGLN2
SCHEMBL2649287 0.80 KIF11 (0.44) KIF11MAOAMAOBPTGS1MMP3
SCHEMBL34472104 0.80 EGLN2 (0.44) KIF11MAOAMAOBPTGS1EGLN2
SCHEMBL20904953 0.78 NPC1 (0.46) PTGS1TSHRGCGRMAPK14
SCHEMBL31067176 0.78 NPC1 (0.46) PTGS1TSHRGCGRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670507-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-06 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed