Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468784 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL19339927 | 0.85 | FOLH1 (0.40) | GNPATALDH1A1FOLH1NOD1TGFBR1 | |
| SCHEMBL16745724 | 0.84 | GNPAT (0.62) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL526519 | 0.80 | MAPT (0.57) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL993144 | 0.80 | MAPT (0.57) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1694958 | 0.80 | MAPT (0.57) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL137690 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064031 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL243250 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL15691994 | 0.77 | FOLH1 (0.50) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123836-A2 | HERBOXIDIENE SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-06-18 | — | — | WO | disclosed |