Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993144 | 1.00 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL1694958 | 1.00 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2323000 | 0.86 | MAPT (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL15423894 | 0.84 | CA12 (0.51) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL14971060 | 0.84 | TGFBR1 (0.44) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL468784 | 0.83 | SMN1; SMN2 (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL16104702 | 0.83 | CA12 (0.51) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL527416 | 0.83 | CA12 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL1293468 | 0.83 | TGFBR1 (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL754070 | 0.83 | TGFBR1 (0.42) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523957-B | The method that one kettle way prepares scheme for lacosamide | 齐鲁天和惠世制药有限公司 | 2017-10-31 | — | — | CN | claimed |
| CN-105523957-A | Method for preparing Lacosamide by one-pot method | QILU TIANHE PHARMACEUTICAL CO LTD | 2016-04-27 | — | — | CN | claimed |
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | claimed |
| EP-2640691-A1 | PROCESS FOR PREPARING LACOSAMIDE | UCB Pharma GmbH (DE) | 2013-09-25 | — | — | EP | claimed |
| EP-2621893-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB Pharma GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| US-20130190533-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-07-25 | — | — | US | claimed |
| EP-2582833-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | Medichem, S.A. (ES) | 2013-04-24 | — | — | EP | claimed |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2013-02-14 | — | — | US | claimed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | claimed |
| WO-2012065891-A1 | PROCESS FOR PREPARING LACOSAMIDE | UCB PHARMA GMBH (DE) | 2012-05-24 | — | — | WO | claimed |
| WO-2012041986-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2012-04-05 | — | — | WO | claimed |
| WO-2011158194-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | MEDICHEM, S.A. (ES) | 2011-12-22 | — | — | WO | claimed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | claimed |
| CN-211595671-U | Chiral amino acid apparatus for producing | 宜昌尚诺德生物医药科技有限公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-3260442-A1 | PROCESS FOR PREPARATION OF OPTICALLY PURE N-SUBSTITUTED-3-METHOXYPROPIONIC ACID DERIVATIVES | SCI Pharmatech, Inc. (TW) | 2017-12-27 | — | — | EP | disclosed |
| US-9790170-B2 | Method for preparing lacosamide | ST PHARM CO., LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| US-20110021482-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2011-01-27 | — | — | US | disclosed |
| US-20110021482-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2011-01-27 | — | — | US | disclosed |
| EP-2262764-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | The University of North Carolina At Chapel Hill (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009145816-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021482-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NAAA, AADAC, GBA1 | MAPT 241/4885KDM4E 3304/4885THRB 2680/4885 |
| US-20130190533-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | BCAT2, BCAT1, HNMT | MAPT 1547/4885KDM4E 1214/4885THRB 2308/4885 |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | AMY1A, PTMA, NAAA | MAPT 3463/4885KDM4E 2800/4885THRB 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.