Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226425 | 0.79 | STS (0.54) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL4100013 | 0.79 | STS (0.69) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL22115171 | 0.74 | STS (0.60) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL16400521 | 0.73 | KMT2A (0.67) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL8283575 | 0.72 | PTPN2 (0.81) | PTPN2PTPN1PTPN6STSNPC1 | |
| SCHEMBL228865 | 0.72 | EED (0.51) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL3850388 | 0.72 | GPR119 (0.49) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL22115157 | 0.71 | STS (0.64) | PTPN2PTPN1PTPN6STSKMT2A | |
| SCHEMBL20615620 | 0.71 | KDM4E (0.64) | KMT2AMAPTMAPK1 | |
| SCHEMBL22797037 | 0.71 | PTPN2 (0.62) | PTPN2PTPN1PTPN6STSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119590-A1 | 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. | 中国科学院上海药物研究所 | 2020-06-18 | — | — | WO | disclosed |