SCHEMBL22115776

SCHEMBL22115776

COCCOC(=O)C1CCCC(C)C1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.36
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.33
AAK1 Q2M2I8 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.32
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526524 0.85 EPHX2 (0.42) EPHX2MEN1KMT2AALDH1A1AAK1
SCHEMBL22115793 0.84 ALDH1A1 (0.42) EPHX2MEN1KMT2AALDH1A1TSHR
SCHEMBL13954785 0.83 EPHX2 (0.36) EPHX2PKMNPSR1HSD17B10MEN1
SCHEMBL3877089 0.82 ALDH1A1 (0.45) EPHX2NPSR1MEN1KMT2AATM
SCHEMBL862098 0.81 ALDH1A1 (0.38) EPHX2KMT2AATMALDH1A1TSHR
SCHEMBL845063 0.81 ALDH1A1 (0.38) EPHX2KMT2AATMALDH1A1TSHR
SCHEMBL3290824 0.81 ALDH1A1 (0.49) MEN1KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL13369529 0.81 ALDH1A1 (0.49) MEN1KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL22420090 0.81 ALDH1A1 (0.49) MEN1KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL2874176 0.81 EPHX2 (0.35) EPHX2MEN1KMT2AALDH1A1AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111349185-B Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔能源有限公司 2023-02-03 CN disclosed
US-11427657-B2 Solid catalyst for propylene polymerization and method of producing block copolymer using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-08-30 US disclosed
CN-111349185-A Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔有限公司 2020-06-30 CN disclosed
US-20200199266-A1 Solid Catalyst For Propylene Polymerization And Method Of Producing Block Copolymer Using The Same HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2020-06-25 US disclosed
EP-3670546-A1 SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND METHOD OF PRODUCING BLOCK COPOLYMER USING THE SAME Hanwha Total Petrochemical Co., Ltd. (KR) 2020-06-24 EP disclosed