SCHEMBL22117566

SCHEMBL22117566

CC(C)CC[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.53
▸ NPY1R P25929 8/20 0.53
▸ NPY5R Q15761 6/20 0.53
▸ NPY2R P49146 5/20 0.53
▸ KISS1R Q969F8 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117569 1.00 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117382 0.97 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117383 0.97 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117541 0.94 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117539 0.94 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL28652782 0.90 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL28652783 0.90 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29461968 0.90 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30592738 0.90 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29461983 0.90 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT NPY4R 2540/4885NPY1R 2382/4885NPY5R 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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