Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.53 |
| ▸ | NPY1R | P25929 | 7/20 | 0.53 |
| ▸ | NPY2R | P49146 | 5/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117584 | 1.00 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117443 | 0.93 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117442 | 0.93 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117549 | 0.93 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117534 | 0.93 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117536 | 0.93 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL31679020 | 0.91 | CTSL (0.53) | NPY4RNPY1RNPY2RNPY5RCTSL | |
| SCHEMBL22117807 | 0.90 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117809 | 0.90 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117385 | 0.87 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5RCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |