Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.46 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118783 | 0.85 | ALDH1A1 (0.50) | HTTSTING1IRF3BRD4L3MBTL1 | |
| SCHEMBL10686084 | 0.78 | HPGD (0.52) | L3MBTL1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22118988 | 0.75 | STING1 (0.66) | STING1IRF3 | |
| SCHEMBL22120992 | 0.74 | HTT (0.52) | HTTKMT2ALMNASMN1; SMN2TGM2 | |
| SCHEMBL23971179 | 0.73 | PTGER4 (0.49) | HTTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL16915012 | 0.73 | HTT (0.51) | HTTBRD4L3MBTL1MEN1KMT2A | |
| SCHEMBL8100512 | 0.72 | HTT (0.60) | HTTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL2063856 | 0.72 | HPGD (0.65) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL22135029 | 0.72 | STING1 (0.44) | STING1BRD4MEN1KMT2A | |
| SCHEMBL19437440 | 0.72 | MEN1 (0.43) | HTTMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |