SCHEMBL22119003

SCHEMBL22119003

CCCn1nc(C)cc1Nc1nc2cc(C(N)=O)cc(CN3CCOCC3)c2n1CCC

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135195 0.87 STING1 (0.71) STING1
SCHEMBL19437588 0.85 STING1 (0.77) STING1
SCHEMBL22135905 0.83 STING1 (0.54) STING1
SCHEMBL22119468 0.82 STING1 (0.67) STING1
SCHEMBL22136248 0.82 STING1 (0.49) STING1
SCHEMBL19437516 0.80 STING1 (0.46) STING1
SCHEMBL22135916 0.79 STING1 (0.54) STING1
SCHEMBL22135019 0.78 STING1 (0.72) STING1
SCHEMBL22135897 0.77 STING1 (0.55) STING1
SCHEMBL22136127 0.77 STING1 (0.53) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 — — WO disclosed
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