Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.49 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135905 | 0.88 | STING1 (0.54) | STING1MAP3K7CASP1CASP7HSD17B10 | |
| SCHEMBL19437516 | 0.84 | STING1 (0.46) | STING1KDM4EMAPT | |
| SCHEMBL22135916 | 0.82 | STING1 (0.54) | STING1MAP3K7 | |
| SCHEMBL22119003 | 0.82 | STING1 (0.56) | STING1 | |
| SCHEMBL22135920 | 0.81 | STING1 (0.55) | STING1MAP3K7 | |
| SCHEMBL22135899 | 0.81 | STING1 (0.53) | STING1 | |
| SCHEMBL22136127 | 0.81 | STING1 (0.53) | STING1MAP3K7 | |
| SCHEMBL22135897 | 0.81 | STING1 (0.55) | STING1MAP3K7 | |
| SCHEMBL22135195 | 0.81 | STING1 (0.71) | STING1 | |
| SCHEMBL22136257 | 0.80 | STING1 (0.56) | STING1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |