Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209226 | 0.86 | HRH3 (0.51) | HRH3EPHX2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL1381470 | 0.86 | HRH3 (0.63) | HRH3EPHX2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL2208923 | 0.82 | HRH3 (0.55) | HRH3AVPR1B | |
| SCHEMBL2209034 | 0.79 | HRH3 (0.52) | HRH3 | |
| SCHEMBL2209038 | 0.76 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL2211880 | 0.75 | HRH3 (0.51) | HRH3AVPR1B | |
| SCHEMBL2208108 | 0.75 | HRH3 (0.85) | HRH3 | |
| SCHEMBL2208812 | 0.74 | HRH3 (0.54) | HRH3KCNH2AVPR1B | |
| SCHEMBL4502549 | 0.73 | HRH3 (0.67) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL2208642 | 0.73 | HRH3 (0.78) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | claimed |