Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.58 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.58 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.58 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | S100B | P04271 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | AOC1 | P19801 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633125 | 0.92 | PRMT1 (0.73) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL22120014 | 0.92 | PRMT1 (0.73) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL6949740 | 0.92 | PRMT1 (0.50) | PRMT1F2ST14PLAUPRMT5 | |
| Hydrochloric Acid SCHEMBL7083326 | 0.91 | PRSS1 (0.51) | PRMT1F2ST14PLAUPRMT5 | |
| Hydrochloric Acid SCHEMBL6949761 | 0.91 | PRSS1 (0.51) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL12461767 | 0.90 | PRSS1 (0.47) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL19486286 | 0.88 | PRSS1 (0.50) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL15149527 | 0.88 | PRSS1 (0.46) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL15142491 | 0.86 | PRSS1 (0.49) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL19486284 | 0.86 | MAPT (0.46) | PRMT1F2ST14PLAUPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077235-A1 | PENTAMIDINE ANALOGS | MCMASTER UNIVERSITY (CA) | 2023-05-11 | — | — | WO | disclosed |
| EP-3897600-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | Auransa Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132636-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | AURANSA INC. (US) | 2020-06-25 | — | — | WO | disclosed |