Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486286 | 0.92 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL6949740 | 0.89 | PRMT1 (0.50) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL6949761 | 0.88 | PRSS1 (0.51) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL7083326 | 0.88 | PRSS1 (0.51) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL22120216 | 0.86 | PRMT1 (0.58) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL15149527 | 0.85 | PRSS1 (0.46) | PRSS1FURINTMPRSS2PRMT1F2 | |
| SCHEMBL12461767 | 0.83 | PRSS1 (0.47) | PRSS1FURINTMPRSS2PRMT1F2 | |
| SCHEMBL15142491 | 0.83 | PRSS1 (0.49) | PRSS1FURINTMPRSS2PRMT1F2 | |
| SCHEMBL19481639 | 0.83 | NNMT (0.44) | MAPTPRSS1PRSS2PRSS3FURIN | |
| SCHEMBL25404032 | 0.81 | FURIN (0.48) | MAPTPRSS1PRSS2PRSS3FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2017-10-19 | — | — | US | disclosed |
| WO-2017180794-A1 | DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS | SKYLINE ANTIINFECTIVES, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | DDOST, LBR, STS | MAPT 4127/4885PRSS1 295/4885PRSS2 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.