Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121025 | 1.00 | MAPT (0.61) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL22121038 | 0.91 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL22121037 | 0.91 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL21616402 | 0.88 | HCAR3 (0.60) | MAPTLMNAKMT2AHCAR3GAA | |
| SCHEMBL28419206 | 0.87 | KMT2A (0.52) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL29405983 | 0.87 | KMT2A (0.52) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL19451471 | 0.87 | KMT2A (0.52) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL753425 | 0.83 | KMT2A (0.72) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL22121203 | 0.80 | KMT2A (0.47) | MAPTALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL22121338 | 0.78 | HCAR3 (0.59) | MAPTALDH1A1RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |