Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199065 | 0.87 | CXCR4 (0.85) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL6196399 | 0.84 | CXCR4 (1.00) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL7164854 | 0.84 | CXCR4 (0.93) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL6197634 | 0.82 | CXCR4 (0.96) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL14447553 | 0.82 | CXCR4 (0.96) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL13801517 | 0.82 | CXCR4 (0.77) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL22121595 | 0.82 | HTT (0.66) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL1520381 | 0.81 | POLB (1.00) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL11715808 | 0.79 | CXCR4 (0.72) | CXCR4POLBTLR8HTTCYP1A2 | |
| SCHEMBL17329351 | 0.79 | CXCR4 (0.72) | CXCR4POLBTLR8HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |