Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.66 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119062 | 0.92 | STING1 (0.69) | STING1TBK1KMT2AJAK2JAK1 | |
| SCHEMBL22121551 | 0.91 | STING1 (0.68) | STING1TBK1EHMT2KMT2AJAK2 | |
| SCHEMBL22121188 | 0.90 | STING1 (0.54) | STING1TBK1KDM4EKMT2APTGER4 | |
| SCHEMBL22121578 | 0.89 | STING1 (0.69) | STING1TBK1KMT2AJAK2JAK1 | |
| SCHEMBL22121136 | 0.87 | STING1 (0.67) | STING1TBK1KMT2AJAK2JAK1 | |
| SCHEMBL22121286 | 0.87 | STING1 (0.50) | STING1TBK1KDM4EKMT2APTGER4 | |
| Hydrochloric Acid SCHEMBL22121564 | 0.86 | STING1 (0.66) | STING1TBK1KMT2AJAK2JAK1 | |
| SCHEMBL31494201 | 0.86 | STING1 (0.90) | STING1TBK1 | |
| SCHEMBL19451506 | 0.86 | STING1 (0.90) | STING1TBK1 | |
| SCHEMBL22118964 | 0.85 | STING1 (0.78) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |