Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123534 | 1.00 | PTK6 (0.33) | PTK6TTKJAK2JAK1 | |
| Formic Acid SCHEMBL30171767 | 0.98 | PTK6 (0.32) | PTK6TTKJAK2JAK1 | |
| SCHEMBL22123824 | 0.92 | PTK6 (0.37) | PTK6TTKJAK2JAK1 | |
| SCHEMBL22123823 | 0.92 | PTK6 (0.37) | PTK6TTKJAK2JAK1 | |
| SCHEMBL30385502 | 0.92 | PTK6 (0.37) | PTK6TTKJAK2JAK1 | |
| SCHEMBL28982170 | 0.91 | JAK2 (0.33) | PTK6TTKJAK2JAK1 | |
| SCHEMBL28982168 | 0.91 | JAK2 (0.33) | PTK6TTKJAK2JAK1 | |
| Formic Acid SCHEMBL30171911 | 0.90 | PTK6 (0.36) | PTK6TTKJAK2JAK1 | |
| SCHEMBL25176001 | 0.90 | — | — | |
| Trifluoroacetic Acid SCHEMBL28982197 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |