Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 20/20 | 0.44 |
| ▸ | LCK | P06239 | 8/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177693 | 1.00 | PTK6 (0.44) | PTK6LCKAURKB | |
| SCHEMBL22124034 | 1.00 | PTK6 (0.44) | PTK6LCKAURKB | |
| SCHEMBL22124238 | 1.00 | PTK6 (0.44) | PTK6LCKAURKB | |
| SCHEMBL30177798 | 1.00 | PTK6 (0.44) | PTK6LCKAURKB | |
| Trifluoroacetic Acid SCHEMBL25174610 | 0.97 | PTK6 (0.41) | PTK6LCKAURKB | |
| Trifluoroacetic Acid SCHEMBL30401969 | 0.97 | PTK6 (0.41) | PTK6LCKAURKB | |
| SCHEMBL22125144 | 0.95 | PTK6 (0.42) | PTK6LCKAURKB | |
| SCHEMBL22125059 | 0.95 | PTK6 (0.42) | PTK6LCKAURKB | |
| SCHEMBL22124065 | 0.95 | PTK6 (0.42) | PTK6LCKAURKB | |
| SCHEMBL30193224 | 0.95 | PTK6 (0.42) | PTK6LCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | claimed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | claimed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | claimed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |