Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.35 |
| ▸ | TTK | P33981 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124065 | 1.00 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL30193224 | 1.00 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22125144 | 1.00 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| Trifluoroacetic Acid SCHEMBL25168714 | 0.97 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22124034 | 0.95 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL30177798 | 0.95 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL30177693 | 0.95 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL22124238 | 0.95 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL22124014 | 0.95 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL22124335 | 0.94 | PTK6 (0.42) | PTK6AURKBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | claimed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | claimed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | claimed |
| US-20230011869-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-01-12 | — | — | US | disclosed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230011869-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | MRPL21, O60361, MYD88 | PTK6 2201/4885AURKB 3265/4885LCK 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.