Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | JAK1 | P23458 | 5/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177671 | 1.00 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL30177956 | 1.00 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL24977845 | 0.93 | PTK6 (0.51) | PTK6AURKBLCK | |
| SCHEMBL22124433 | 0.92 | PTK6 (0.44) | PTK6AURKBLCKTTK | |
| SCHEMBL30177831 | 0.92 | PTK6 (0.44) | PTK6AURKBLCKTTK | |
| SCHEMBL30177783 | 0.92 | PTK6 (0.44) | PTK6AURKBLCKTTK | |
| SCHEMBL22123909 | 0.92 | PTK6 (0.50) | PTK6AURKBLCKTTK | |
| Formic Acid SCHEMBL30172051 | 0.89 | PTK6 (0.48) | PTK6AURKBLCKTTK | |
| SCHEMBL22123779 | 0.89 | PTK6 (0.52) | PTK6AURKBLCKTTK | |
| SCHEMBL22142840 | 0.88 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |