Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752919 | 0.95 | NPC1 (0.43) | NPC1NAAASPHK1GAA | |
| SCHEMBL1258617 | 0.93 | NPC1 (0.47) | NPC1NAAASPHK1 | |
| SCHEMBL21244129 | 0.91 | NPC1 (0.32) | NPC1 | |
| SCHEMBL1901243 | 0.91 | NPC1 (0.45) | NPC1NAAASPHK1GAA | |
| SCHEMBL8614030 | 0.91 | NPC1 (0.45) | NPC1NAAASPHK1GAA | |
| SCHEMBL3098673 | 0.90 | — | — | |
| SCHEMBL10679303 | 0.90 | EPHX2 (0.33) | NPC1SPHK1GAA | |
| SCHEMBL10684492 | 0.88 | GAA (0.35) | NPC1SPHK1GAA | |
| SCHEMBL10687104 | 0.88 | GAA (0.35) | NPC1SPHK1GAA | |
| SCHEMBL13096848 | 0.88 | GAA (0.35) | NPC1SPHK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898633-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-113474348-A | Substituted oxopyridine derivatives | 拜耳公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |