Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614030 | 1.00 | NPC1 (0.45) | NPC1NAAAEPHX1PRKCAALDH1A1 | |
| SCHEMBL1258617 | 0.98 | NPC1 (0.47) | NPC1NAAAEPHX1PRKCAALDH1A1 | |
| SCHEMBL3752919 | 0.96 | NPC1 (0.43) | NPC1NAAAEPHX1PRKCAALDH1A1 | |
| Bicarbonate SCHEMBL10534241 | 0.92 | NAAA (0.40) | NPC1NAAAEPHX1PRKCAALDH1A1 | |
| SCHEMBL22124333 | 0.91 | NPC1 (0.39) | NPC1NAAASPHK1GAA | |
| SCHEMBL3345126 | 0.91 | NPC1 (0.48) | NPC1NAAAEPHX1 | |
| SCHEMBL386704 | 0.91 | NPC1 (0.48) | NPC1NAAAEPHX1 | |
| SCHEMBL10684492 | 0.89 | GAA (0.35) | NPC1ALDH1A1SPHK1GAAKMT2A | |
| SCHEMBL1444884 | 0.89 | NPC1 (0.45) | NPC1NAAAALDH1A1 | |
| SCHEMBL10687104 | 0.89 | GAA (0.35) | NPC1ALDH1A1SPHK1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102630222-B | Process for preparing diols by hydrogenation of carboxylic acid-containing mixtures using cobalt-containing catalysts | BASF SE | 2015-04-08 | — | — | CN | disclosed |
| EP-2504300-B1 | METHOD FOR PRODUCING DIOLS BY HYDROGENATION OF A CARBOXYLIC ACID-CONTAINING MIXTURE USING COBALT-CONTAINING CATALYSTS | BASF SE (DE) | 2014-01-15 | — | — | EP | disclosed |
| US-8383866-B2 | Process for preparing diols by hydrogenating a carboxylic acid-comprising mixture by means of cobalt-comprising catalysts | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2504300-A1 | METHOD FOR PRODUCING DIOLS BY HYDROGENATION OF A CARBOXYLIC ACID-CONTAINING MIXTURE USING COBALT-CONTAINING CATALYSTS | BASF SE (DE) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011064182-A1 | METHOD FOR PRODUCING DIOLS BY HYDROGENATION OF A CARBOXYLIC ACID-CONTAINING MIXTURE USING COBALT-CONTAINING CATALYSTS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| US-20110124926-A1 | PROCESS FOR PREPARING DIOLS BY HYDROGENATING A CARBOXYLIC ACID-COMPRISING MIXTURE BY MEANS OF COBALT-COMPRISING CATALYSTS | BASF SE (DE) | 2011-05-26 | — | — | US | disclosed |