SCHEMBL22124451

SCHEMBL22124451

CC(C)[Si](NC(=O)O)(C(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24436902 0.77 KDM4E (0.35)
SCHEMBL27534228 0.74 LMNA (0.33)
SCHEMBL25166720 0.67
Hydrochloric Acid SCHEMBL25166726 0.65
SCHEMBL1320483 0.65
SCHEMBL150170 0.58
SCHEMBL7525656 0.58 CYP2D6 (0.41) CYP2D6CYP2C19TP53
SCHEMBL28719441 0.58 CYP2D6 (0.41) CYP2D6CYP2C19TP53
SCHEMBL42490 0.58
Isobutane SCHEMBL6337855 0.57 CA1 (0.56) CYP2D6CYP2C19TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12215100-B2 Anticancer compounds PHARMA MAR, S.A. (ES) 2025-02-04 US disclosed
EP-3898613-B1 ANTICANCER COMPOUNDS PHARMA MAR SA (ES) 2023-08-09 EP disclosed
US-20220056021-A1 ANTICANCER COMPOUNDS PHARMA MAR, S.A. (ES) 2022-02-24 US disclosed
EP-3898613-A1 ANTICANCER COMPOUNDS Pharma Mar S.A. (ES) 2021-10-27 EP disclosed
WO-2020127194-A1 ANTICANCER COMPOUNDS PHARMA MAR, S.A. (ES) 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220056021-A1 ANTICANCER COMPOUNDS TP53, MCL1, MYC CYP2D6 1373/4885CYP2C19 2602/4885TP53 1/4885
US-12215100-B2 Anticancer compounds TP53, MCL1, MYC CYP2D6 1371/4885CYP2C19 2600/4885TP53 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.