Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.69 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.69 |
| ▸ | KCNQ3 | O43525 | 8/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 6/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599834 | 0.88 | SMARCA2 (0.86) | SMARCA2SMARCA4CNR1 | |
| SCHEMBL22154751 | 0.87 | SMARCA2 (0.64) | SMARCA2SMARCA4 | |
| SCHEMBL6361424 | 0.87 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL30568974 | 0.87 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL22125204 | 0.84 | SMARCA2 (0.74) | SMARCA2SMARCA4CNR1 | |
| SCHEMBL11047103 | 0.84 | SMARCA2 (0.79) | SMARCA2SMARCA4CNR1 | |
| SCHEMBL22155020 | 0.83 | SMARCA2 (0.76) | SMARCA2SMARCA4KCNQ3KCNQ2KCNE1 | |
| SCHEMBL22125246 | 0.83 | SMARCA2 (0.59) | SMARCA2SMARCA4KCNQ3KCNQ2 | |
| SCHEMBL27954487 | 0.83 | MEN1 (0.64) | SMARCA2SMARCA4CNR1 | |
| SCHEMBL27910562 | 0.83 | EPHX1 (0.71) | KCNQ3KCNQ2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | claimed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |