SCHEMBL221255

SCHEMBL221255

CCCCCCCCCCCC[C](CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
TSHR P16473 5/20 0.57
THRB P10828 1/20 0.57
GPR84 Q9NQS5 7/20 0.55
PPARG P37231 7/20 0.55
PPARD Q03181 7/20 0.55
PPARA Q07869 7/20 0.55
HDAC11 Q96DB2 5/20 0.55
PTPN1 P18031 3/20 0.55
ALDH1A1 P00352 2/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
FABP4 P15090 2/20 0.55
SLC22A6 Q4U2R8 1/20 0.55
SLC22A8 Q8TCC7 1/20 0.55
MEN1 O00255 1/20 0.55
ESR1 P03372 1/20 0.55
ALOX15 P16050 1/20 0.55
PDE4A P27815 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5394178 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL9284134 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL1982513 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL6046243 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL11314393 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL7211309 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL17842045 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL7627142 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL11797136 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL7525346 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541177-B2 Methods for identifying pathological conditions in a female subject COMMON SENSE, LTD. (IL) 2009-06-02 US claimed
EP-0184465-B1 A THERMOPLASTIC POLYURETHANE PRODUCT Deseret Medical, Inc. (US) 1990-03-07 EP claimed
CN-116948731-A Rust-proof lubricating oil and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-10-27 CN disclosed
US-9546321-B2 Compositions and methods for selectively etching titanium nitride ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2017-01-17 US disclosed
US-20150027978-A1 COMPOSITIONS AND METHODS FOR SELECTIVELY ETCHING TITANIUM NITRIDE ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2015-01-29 US disclosed
US-20120003685-A1 DIAGNOSTIC COMPOSITION AND ARTICLE FOR MONITORING INTRAVAGINAL INFECTIONS COMMON SENSE LTD. (IL) 2012-01-05 US disclosed
US-7947467-B2 Methods for monitoring pathological conditions in a female subject COMMON SENSE LTD. (IL) 2011-05-24 US disclosed
US-7915412-B2 Reacting 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrrido[1,2-a]-pyrimidin-4-one, and 6-fluoro-3-piperidino-1,2-benisoxazol, in the presence of an inorganic base. TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2011-03-29 US disclosed
US-20100136707-A1 METHODS FOR MONITORING PATHOLOGICAL CONDITIONS IN A FEMALE SUBJECT COMMON SENSE LTD. (IL) 2010-06-03 US disclosed
US-7608180-B2 Amperometric sensor DREW SCIENTIFIC HOLDINGS, INC. (US) 2009-10-27 US disclosed
EP-1194585-B1 AMPEROMETRIC SENSOR DREW SCIENT CO LTD (US) 2008-11-19 EP disclosed
US-5863972-A POLYUREAURETHANE COPOLYMERS AND NONIONIC IONOPHORES WITH CALCIUM ION CHIRON DIAGNOSTICS CORPORATION (US) 1999-01-26 US disclosed
EP-0876363-A1 POLYMER-BOUND FLUOROPHORES AS OPTICAL ION SENSORS Novartis AG (CH) 1998-11-11 EP disclosed
EP-0758450-B1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS CIBA GEIGY AG (CH) 1998-08-05 EP disclosed
EP-0792454-A1 RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca?++ IONS Chiron Diagnostics Corporation (US) 1997-09-03 EP disclosed
WO-1997011067-A1 POLYMER-BOUND FLUOROPHORES AS OPTICAL ION SENSORS NOVARTIS AG (CH) 1997-03-27 WO disclosed
EP-0758450-A1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS Novartis AG (CH) 1997-02-19 EP disclosed
WO-1996015443-A1 RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca++ IONS CHIRON DIAGNOSTICS CORPORATION_ (CH) 1996-05-23 WO disclosed
WO-1995026501-A1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS CIBA-GEIGY AG (CH) 1995-10-05 WO disclosed
EP-0623599-A1 Optical sensors for the determination of cations CIBA-GEIGY AG (CH) 1994-11-09 EP disclosed