SCHEMBL22129133

SCHEMBL22129133

O=C(Nc1cnccc1Nc1ccccc1)c1ccc(Br)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.60
CYP11B2 P19099 1/20 0.60
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
KDM4D Q6B0I6 1/20 0.53
KDM4C Q9H3R0 1/20 0.53
TP53 P04637 2/20 0.52
NAMPT P43490 3/20 0.50
HTT P42858 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
PTGS1 P23219 2/20 0.47
PTGS2 P35354 2/20 0.47
JAK2 O60674 1/20 0.47
TYK2 P29597 1/20 0.47
DNMT1 P26358 1/20 0.46
DNMT3A Q9Y6K1 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339194 0.84 MEN1 (0.71) CYP11B1CYP11B2MEN1KMT2ATP53
SCHEMBL12946172 0.81 MEN1 (0.66) MEN1KMT2ATP53NPC1RAB9A
SCHEMBL12946208 0.80 MEN1 (0.69) CYP11B1CYP11B2MEN1KMT2ATP53
SCHEMBL338138 0.79 MEN1 (0.67) MEN1KMT2ATP53RAB9ATDP1
SCHEMBL27616779 0.78 POLB (0.63) CYP11B1CYP11B2MEN1KMT2AKDM4D
SCHEMBL14542346 0.77 CYP11B1 (0.57) CYP11B1CYP11B2MEN1KMT2AKDM4D
SCHEMBL14363394 0.77 MEN1 (0.64) MEN1KMT2ATP53NPC1RAB9A
SCHEMBL17624571 0.77 CYP11B1 (0.51) CYP11B1CYP11B2MEN1KMT2ANAMPT
SCHEMBL22129138 0.76 MEN1 (0.59) CYP11B1CYP11B2MEN1KMT2ATP53
SCHEMBL31454188 0.76 MEN1 (0.59) CYP11B1CYP11B2MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333615-B Heterocyclic compound and organic light-emitting device including the same 三星显示有限公司 2025-02-28 CN disclosed
US-20200203630-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2020-06-25 US disclosed
US-20200203630-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2020-06-25 US disclosed