SCHEMBL339194

SCHEMBL339194

O=C(Nc1ccccc1Nc1ccccc1)c1ccc(Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.71
KMT2A Q03164 6/20 0.71
TP53 P04637 2/20 0.62
SIRT2 Q8IXJ6 1/20 0.55
HDAC2 Q92769 3/20 0.54
HDAC1 Q13547 2/20 0.54
HDAC3 O15379 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.53
POLB P06746 2/20 0.51
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
MAPT P10636 2/20 0.50
PTPN1 P18031 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12946208 0.95 MEN1 (0.69) MEN1KMT2ATP53SIRT2HDAC1
SCHEMBL338138 0.94 MEN1 (0.67) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL14363394 0.91 MEN1 (0.64) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL12946172 0.89 MEN1 (0.66) MEN1KMT2ATP53HDAC2HDAC1
SCHEMBL6140750 0.88 SIRT2 (0.59) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL15888707 0.87 TP53 (0.58) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL15770775 0.86 MEN1 (0.53) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL338745 0.85 SIRT2 (0.56) MEN1KMT2ATP53SIRT2HDAC2
SCHEMBL22129133 0.84 CYP11B1 (0.60) MEN1KMT2ATP53RAB9ANPC1
SCHEMBL16442425 0.84 MAPT (0.62) MEN1KMT2ATP53HDAC2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11637256-B2 Quantum dots with charge-transporting ligands NANOSYS, INC. (US) 2023-04-25 US disclosed
US-11637256-B2 Quantum dots with charge-transporting ligands NANOSYS, INC. (US) 2023-04-25 US disclosed
CN-107820497-B Imidazopyrazine derivatives for electronic devices 陶氏环球技术有限责任公司 2021-06-08 CN disclosed
CN-107602553-B Organic small molecule electron transport material and preparation method and application thereof 华南理工大学 2020-11-24 CN disclosed
US-10786683-B2 Light-emitting devices for wound healing NITTO DENKO CORPORATION (JP) 2020-09-29 US disclosed
EP-3313843-B1 IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-11 EP disclosed
WO-2020040982-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 WO disclosed
WO-2020040982-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 WO disclosed
US-20200067006-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 US disclosed
US-20200067006-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 US disclosed
CN-101812021-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2010-08-25 CN disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
CN-101503393-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-08-12 CN disclosed
US-20090184633-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-07-23 US disclosed
US-20090184633-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-07-23 US disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
CN-1784388-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2006-06-07 CN disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184633-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative H1-0, NQO2, GDI1 MEN1 997/4885KMT2A 320/4885TP53 4781/4885
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG MEN1 2259/4885KMT2A 526/4885TP53 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.