SCHEMBL22129342

SCHEMBL22129342

CN1CCc2ccc(OCCCOc3ccc4c(c3)C(=O)N(C)CC4)cc2C1=O

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038441 0.93 DRD2 (0.64) DRD2
SCHEMBL29678818 0.93 DRD2 (0.64) DRD2
SCHEMBL22163345 0.92 DRD2 (0.62) DRD2
SCHEMBL1037463 0.92 DRD2 (0.62) DRD2
SCHEMBL4328789 0.90 DRD2 (0.60) DRD2
SCHEMBL31438780 0.83 MEN1 (0.62) DRD2
SCHEMBL1036238 0.83 MEN1 (0.62) DRD2
SCHEMBL20512980 0.83 DRD2 (0.81) DRD2
SCHEMBL29786358 0.83 DRD2 (0.81) DRD2
SCHEMBL20512939 0.82 DRD2 (1.00) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220048887-A1 IMPURITIES OF AMIDE-LIKE DERIVATIVES AND USE THEREOF NHWA PHARMA. CORPORATION (CN) 2022-02-17 US disclosed
US-20220048887-A1 IMPURITIES OF AMIDE-LIKE DERIVATIVES AND USE THEREOF NHWA PHARMA. CORPORATION (CN) 2022-02-17 US disclosed
EP-3901149-A1 IMPURITIES OF AMIDE DERIVATIVES AND USE THEREOF NHWA Pharma Corporation (CN) 2021-10-27 EP disclosed
EP-3901149-A1 IMPURITIES OF AMIDE DERIVATIVES AND USE THEREOF NHWA Pharma Corporation (CN) 2021-10-27 EP disclosed
CN-113195486-A Impurities of amide derivatives and application thereof 江苏恩华药业股份有限公司 2021-07-30 CN disclosed
WO-2020125580-A1 IMPURITIES OF AMIDE DERIVATIVES AND USE THEREOF 江苏恩华药业股份有限公司 2020-06-25 WO disclosed
WO-2020125580-A1 IMPURITIES OF AMIDE DERIVATIVES AND USE THEREOF 江苏恩华药业股份有限公司 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048887-A1 IMPURITIES OF AMIDE-LIKE DERIVATIVES AND USE THEREOF NOTUM, CYP51A1, HADHB DRD2 2480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.