Isothiocyanate

Isothiocyanate

SCHEMBL22129485

CC.N=C=S.N=C=S.N=C=S

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isothiocyanate SCHEMBL6080160 1.00
Isothiocyanate SCHEMBL2134259 1.00
Isothiocyanate SCHEMBL8940171 0.87 ALDH1A1 (0.43) ALDH1A1LMNA
Isothiocyanate SCHEMBL133963 0.87
Isothiocyanate SCHEMBL4002 0.87
Isothiocyanate SCHEMBL331482 0.87
Isothiocyanate SCHEMBL28582970 0.82 ALDH1A1 (0.30) ALDH1A1LMNA
Isothiocyanate SCHEMBL17261553 0.82
Methylisothiocyanate SCHEMBL8675064 0.82
Isothiocyanate SCHEMBL23931191 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111349093-B 5, 6-bicyclic compounds as WNT signal pathway inhibitors and medical application thereof 汇瀚医疗科技有限公司 2021-07-02 CN disclosed
CN-111349093-A 5, 6-bicyclic compounds as WNT signal pathway inhibitors and medical application thereof 汇瀚医疗科技有限公司 2020-06-30 CN disclosed
WO-2020125759-A1 COMPOUND AS WNT SIGNAL PATHWAY INHIBITOR AND MEDICAL USE THEREOF 汇瀚医疗科技有限公司 2020-06-25 WO disclosed