SCHEMBL22129658

SCHEMBL22129658

CN1CCCCCC1=O.O=C1CCCCN1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.50
BRD2 P25440 1/20 0.50
ALDH1A1 P00352 4/20 0.49
HPGD P15428 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C19 P33261 1/20 0.48
TP53 P04637 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
AKR1C3 P42330 2/20 0.47
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
BRDT Q58F21 1/20 0.44
MAPT P10636 1/20 0.44
HSD17B10 Q99714 1/20 0.44
BRD9 Q9H8M2 1/20 0.44
DRD2 P14416 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1626841 0.90 ALDH1A1 (0.58) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
SCHEMBL329316 0.90 ALDH1A1 (0.58) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
Methylpyrrolidone SCHEMBL28278382 0.89 BRD4 (0.57) BRD4BRD2ALDH1A1HPGDCYP1A2
SCHEMBL76559 0.88 ALDH1A1 (0.59) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
SCHEMBL27409503 0.88 ALDH1A1 (0.59) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL7459714 0.86 ALDH1A1 (0.58) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
SCHEMBL136476 0.82 ALDH1A1 (0.67) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
SCHEMBL20261896 0.82 TP53 (0.54) BRD4ALDH1A1HPGDCYP1A2CYP2D6
Hydrochloric Acid SCHEMBL7466356 0.81 ALDH1A1 (0.65) ALDH1A1HPGDCYP1A2CYP2D6CYP2C9
Tannin Pyrogallol SCHEMBL29240161 0.80 BRD4 (0.57) BRD4BRD2ALDH1A1HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021111693-A1 TIRE 住友ゴム工業株式会社 2021-06-10 WO disclosed
WO-2020129356-A1 TIRE 住友ゴム工業株式会社 2020-06-25 WO disclosed