Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | ACR | P10323 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572552 | 1.00 | KMT2A (0.70) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL12768510 | 1.00 | KMT2A (0.70) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL12768363 | 0.94 | KMT2A (0.78) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL1531938 | 0.94 | KMT2A (0.78) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL13531297 | 0.91 | KMT2A (0.70) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL1531771 | 0.91 | MEN1 (0.73) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL12769300 | 0.90 | KMT2A (0.60) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL13572578 | 0.90 | KMT2A (0.60) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL22089857 | 0.90 | MEN1 (0.87) | KMT2AMEN1NPC1LMNASMN1; SMN2 | |
| SCHEMBL22102520 | 0.90 | KMT2A (0.71) | KMT2AMEN1NPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431039-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120002141-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120002141-A1 | MESOGENIC STABILIZERS | BMI1, METTL14, PYM1 | KMT2A 293/4885MEN1 8/4885NPC1 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.