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Sugi Predict / Targets / METTL14

METTL14

N(6)-adenosine-methyltransferase non-catalyti · Q9HCE5 · METTL14 on Sugi Atlas →

7,381 patent compounds predicted against METTL14, 4,189 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL3072183 SCHEMBL3072183 0.42 6/20
SCHEMBL2259738 SCHEMBL2259738 0.50 5/20
SCHEMBL2251823 SCHEMBL2251823 0.42 5/20
SCHEMBL2251829 SCHEMBL2251829 0.42 5/20
SCHEMBL3399660 SCHEMBL3399660 0.52 4/20
SCHEMBL3401988 SCHEMBL3401988 0.52 4/20
SCHEMBL3429288 SCHEMBL3429288 0.52 4/20
SCHEMBL2449626 SCHEMBL2449626 0.50 4/20
SCHEMBL2771389 SCHEMBL2771389 0.40 4/20
SCHEMBL3082811 SCHEMBL3082811 0.37 4/20
SCHEMBL4364905 SCHEMBL4364905 0.34 4/20
SCHEMBL4372591 SCHEMBL4372591 0.34 4/20
SCHEMBL4370945 SCHEMBL4370945 0.34 4/20
SCHEMBL3425866 SCHEMBL3425866 0.58 3/20
SCHEMBL1881385 SCHEMBL1881385 0.55 3/20
SCHEMBL4305559 SCHEMBL4305559 0.55 3/20
SCHEMBL823315 SCHEMBL823315 0.51 3/20
SCHEMBL3400881 SCHEMBL3400881 0.51 3/20
SCHEMBL3398080 SCHEMBL3398080 0.50 3/20
SCHEMBL3403359 SCHEMBL3403359 0.50 3/20

Clinical trials — most relevant to METTL14 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. PHASE1/PHASE2COMPLETED
Evaluation of Cabozantinib in Metastatic Renal Cell Carcinoma (mRCC) With Brain Metastases PHASE2COMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Prognosis of METTL-14 in Endometrial Carcinoma nanNOT_YET_RECRUITING
Molecular Profiling for Risk Stratification in Appendiceal Cancer nanRECRUITING
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
PLAsma Genomic Testing in Patients With Advanced Non-Small Cell Lung Cancer: The PLAN Study nanUNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Apelin12 in Acne Vulgaris nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 nanCOMPLETED
Search for Bovine miRNA Transference to Humans nanCOMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Dietary Effects of Sulfur Amino Acids nanCOMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients nanCOMPLETED
Association of Brain Derived Neurotrophic Factor (BDNF) rs6265 Gene Polymorphism With Susceptibility to Epilepsy nanUNKNOWN
Follow-up of Covid-19 Long Term Sequelae nanCOMPLETED
Effects of Contact Restrictions During the COVID-19 Pandemic on Newborns and Their Parents nanCOMPLETED
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
DNA Methylation and Perioperative Pain Treatment nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
New Signaling Pathway Targeting Systemic Lupus Erythematosus nanUNKNOWN
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a METTL14 binder may also engage these)

ProteinNameSimilarity
Q3UIK4 — 1.000 Q3UIK4 →
Q6NZ22 — 1.000 Q6NZ22 →
Q5R5N4 — 1.000 Q5R5N4 →
A4IFD8 — 1.000 A4IFD8 →
Q5ZK35 — 0.999 Q5ZK35 →
Q66KJ9 — 0.998 Q66KJ9 →
Q6NU56 — 0.996 Q6NU56 →
Q9VLP7 — 0.995 Q9VLP7 →
P25583 — 0.986 P25583 →
Q8CFQ3 — 0.981 Q8CFQ3 →
Q756E1 — 0.981 Q756E1 →
Q6BX78 — 0.981 Q6BX78 →
Q7SH49 — 0.981 Q7SH49 →
Q7YZT6 — 0.981 Q7YZT6 →
Q5AW75 — 0.980 Q5AW75 →
A5E032 — 0.980 A5E032 →
P32639 — 0.980 P32639 →
P24583 — 0.980 P24583 →
P0CN27 — 0.980 P0CN27 →
O42947 — 0.980 O42947 →
O76512 — 0.980 O76512 →
A8XYX2 — 0.979 A8XYX2 →
A8WRG3 — 0.979 A8WRG3 →
B4P6P7 — 0.979 B4P6P7 →
O82486 — 0.979 O82486 →
Q6BM04 — 0.979 Q6BM04 →
Q9NAA5 — 0.979 Q9NAA5 →
Q99NB9 — 0.979 Q99NB9 →
Q00422 — 0.979 Q00422 →
B4MY63 — 0.979 B4MY63 →