Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELAVL1 | Q15717 | 5/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22130669 | 0.91 | ELAVL1 (0.64) | ELAVL1PTPN1BACE1PTGS2PTPRC | |
| SCHEMBL22130724 | 0.89 | ELAVL1 (1.00) | ELAVL1PTPN1BACE1PTGS2MAPT | |
| SCHEMBL21222570 | 0.77 | ELAVL1 (0.80) | ELAVL1PTPN1BACE1PTPRCPTPRF | |
| SCHEMBL22130709 | 0.76 | ELAVL1 (0.54) | ELAVL1PTPN1BACE1PTGS2PTPRC | |
| SCHEMBL22130712 | 0.75 | ELAVL1 (0.55) | ELAVL1PTPN1PTGS2 | |
| SCHEMBL22130710 | 0.75 | ELAVL1 (0.55) | ELAVL1PTPN1PTGS2PTPRCPTPRF | |
| SCHEMBL22130711 | 0.74 | ELAVL1 (0.54) | ELAVL1PTPN1PTGS2 | |
| SCHEMBL22130718 | 0.74 | ELAVL1 (0.54) | ELAVL1PTGS2KDM4EMAPK1KMT2A | |
| SCHEMBL19737482 | 0.69 | ELAVL1 (0.77) | ELAVL1PTGS2HDAC4HDAC2HDAC8 | |
| SCHEMBL21222504 | 0.68 | HTR6 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | UNIVERSITA' DEGLI STUDI DI TRENTO (IT) | 2020-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689342-B2 | Aza-tanshinone derivatives, process for their preparation and their use in therapy | AZI2, TPMT, TYMS | ELAVL1 2765/4885PTPN1 1930/4885BACE1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.