Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23008894 | 0.84 | PDCD1 (0.34) | PDCD1CD274 | |
| SCHEMBL20386683 | 0.82 | PDCD1 (0.36) | PDCD1CD274 | |
| SCHEMBL20386687 | 0.74 | BACE1 (0.32) | — | |
| SCHEMBL18553109 | 0.71 | TP53 (0.36) | — | |
| SCHEMBL27388757 | 0.67 | KDM4E (0.34) | PDCD1CD274 | |
| SCHEMBL25987138 | 0.62 | — | — | |
| SCHEMBL18541219 | 0.61 | SHBG (0.39) | PDCD1CD274 | |
| SCHEMBL18553121 | 0.61 | BACE1 (0.34) | — | |
| SCHEMBL26036410 | 0.60 | SHBG (0.36) | — | |
| SCHEMBL13937932 | 0.59 | PDE4A (0.47) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325482-B1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-06-24 | — | — | EP | disclosed |