SCHEMBL22133046

CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN2	P17706	2/20	0.58

▸	PTPN1	P18031	2/20	0.58

▸	NPY4R	P50391	14/20	0.57

▸	NPY1R	P25929	9/20	0.57

▸	NPY5R	Q15761	8/20	0.57

▸	NPY2R	P49146	5/20	0.57

▸	KISS1R	Q969F8	1/20	0.56

▸	GNPAT	O15228	1/20	0.55

▸	SIRT5	Q9NXA8	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12792618	0.94	KISS1R (0.62)	PTPN2PTPN1NPY4RNPY1RNPY5R
SCHEMBL13563435	0.94	KISS1R (0.62)	PTPN2PTPN1NPY4RNPY1RNPY5R
SCHEMBL22133047	0.93	NPY4R (0.56)	PTPN2PTPN1NPY4RNPY1RNPY5R
SCHEMBL30045851	0.93	KISS1R (0.61)	PTPN2PTPN1NPY4RNPY1RNPY5R
SCHEMBL19278452	0.90	NPY4R (0.67)	PTPN2PTPN1NPY4RNPY1RNPY5R
SCHEMBL17356289	0.89	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL13563457	0.89	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL18951648	0.89	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL17359203	0.89	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL12794641	0.89	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020131282-A1	MITOCHONDRIA-TARGETING PEPTIDES	STEALTH BIOTHERAPEUTICS CORP. (MC)	2020-06-25	—	—	WO	disclosed