Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100175 | 0.86 | IDO1 (0.52) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL29500531 | 0.71 | L3MBTL1 (0.51) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL22074296 | 0.71 | L3MBTL1 (0.51) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL22074244 | 0.70 | L3MBTL1 (0.49) | HTTL3MBTL1KMT2AALDH1A1NPC1 | |
| SCHEMBL22074273 | 0.69 | L3MBTL1 (0.67) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL29500535 | 0.69 | L3MBTL1 (0.67) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL22074268 | 0.67 | NPC1 (0.43) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL22074243 | 0.66 | L3MBTL1 (0.48) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL29500532 | 0.66 | L3MBTL1 (0.48) | IDO1TDO2HTTL3MBTL1KMT2A | |
| SCHEMBL9642042 | 0.65 | NPC1 (0.58) | IDO1TDO2HTTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131924-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR USE IN TREATING AUTOPHAGY-ASSOCIATED DISORDERS | Biophagy, Inc. (US) | 2020-06-25 | — | — | WO | disclosed |